Proven Pain Relief

  • Multiple clinical studies showed that SUPARTZ FX consistently improved knee pain due to osteoarthritis (12,15,16)
  • In one study, SUPARTZ FX reduced knee pain in patients by 50% from baseline (15)
  • Pain relief can start after the first injection and last for up to six months* (16)

Please note that no single treatment (including SUPARTZ FX) helps every patient the same way.

Help Delay Knee Replacement

  • Treatment with courses of hyaluronic acid, including SUPARTZ FX, may help delay the need for total knee replacement surgery by up to 3.6 years** (17)
  • Treatment with hyaluronic acid can allow you to delay knee replacement surgery while controlling your knee pain so you can remain active


  • In clinical studies, adverse events common to intra-articular treatment were comparable between SUPARTZ FX and saline treated patients (12,13,15,16)
    • In these studies, more people discontinued treatment with saline placebo than those who received SUPARTZ FX therapy (12)
  • Pseudoseptic (acute inflammatory) reactions have NOT been reported in 20 prospective randomized controlled trials of SUPARTZ FX Therapy (18)
  • The FDA reviewed data on more than 8,000 patients prior to approving SUPARTZ FX in the United States (12)

Extensive History of Use

  • More than 300 million SUPARTZ FX injections have been administered worldwide (19)
  • Provides confidence that SUPARTZ FX may safely relieve pain and help you get back to your daily activities

Flexible dosing for an individualized treatment

  • Unlike “one size fits all” HA injection treatments, your physician can tailor the number of injections* depending on your individual needs, to help you break the vicious osteoarthritis cycle
    • You only receive the number of shots that your doctor recommends while your progress can be monitored
*Some patients may experience benefit with as few as 3 injections given at weekly intervals. This has been noted in a study in which patients treated with 3 injections were evaluated for 90 days. (13)
** TKR delay with > or = 5 courses of HA treatment.

SUPARTZ FX is indicated for treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen. You should not use SUPARTZ FX if you have infections or skin diseases at the injection site or allergies to poultry products. SUPARTZ FX is not approved for pregnant or nursing women, or children. Risks can include general knee pain, warmth and redness or pain at the injection site. Full prescribing information can be found here or by contacting customer service at